Bromhexine tablets instructions for use in adults. Bromhexine: instructions for use, analogues and reviews, prices in Russian pharmacies. The tablet form of Bromhexine is available

Bromhexine hydrochloride (bromhexine)

Composition and release form of the drug

◊ Tablets for children white or almost white, round flat-cylindrical with a chamfer and a notch.

Excipients: lactose monohydrate - 80.23 mg, corn starch - 11.54 mg, K25 - 3.46 mg, magnesium stearate - 0.77 mg.

10 pieces. - contour cellular packaging (1) - cardboard packs.
10 pieces. - contour cellular packaging (2) - cardboard packs.
10 pieces. - contour cellular packaging (3) - cardboard packs.
10 pieces. - contour cellular packaging (4) - cardboard packs.
10 pieces. - contour cellular packaging (5) - cardboard packs.
10 pieces. - contour cellular packaging (10) - cardboard packs.
20 pcs. - contour cellular packaging (1) - cardboard packs.
20 pcs. - contour cellular packaging (2) - cardboard packs.
20 pcs. - contour cellular packaging (3) - cardboard packs.
20 pcs. - contour cellular packaging (4) - cardboard packs.
20 pcs. - contour cellular packaging (5) - cardboard packs.
20 pcs. - contour cellular packaging (10) - cardboard packs.
25 pcs. - contour cellular packaging (1) - cardboard packs.
25 pcs. - contour cellular packaging (2) - cardboard packs.
25 pcs. - contour cellular packaging (3) - cardboard packs.
25 pcs. - contour cellular packaging (4) - cardboard packs.
25 pcs. - contour cellular packaging (5) - cardboard packs.
25 pcs. - contour cellular packaging (10) - cardboard packs.
30 pcs. - contour cellular packaging (1) - cardboard packs.
30 pcs. - contour cellular packaging (2) - cardboard packs.
30 pcs. - contour cellular packaging (3) - cardboard packs.
30 pcs. - contour cellular packaging (4) - cardboard packs.
30 pcs. - contour cellular packaging (5) - cardboard packs.
30 pcs. - contour cellular packaging (10) - cardboard packs.
40 pcs. - contour cellular packaging (1) - cardboard packs.
40 pcs. - contour cellular packaging (2) - cardboard packs.
40 pcs. - contour cellular packaging (3) - cardboard packs.
40 pcs. - contour cellular packaging (4) - cardboard packs.
40 pcs. - contour cellular packaging (5) - cardboard packs.
40 pcs. - contour cellular packaging (10) - cardboard packs.
50 pcs. - contour cellular packaging (1) - cardboard packs.
50 pcs. - contour cellular packaging (2) - cardboard packs.
50 pcs. - contour cellular packaging (3) - cardboard packs.
50 pcs. - contour cellular packaging (4) - cardboard packs.
50 pcs. - contour cellular packaging (5) - cardboard packs.
50 pcs. - contour cellular packaging (10) - cardboard packs.
10 pieces. - cans made of polyethylene terephthalate (1) - cardboard packs.
20 pcs. - cans made of polyethylene terephthalate (1) - cardboard packs.
30 pcs. - cans made of polyethylene terephthalate (1) - cardboard packs.
40 pcs. - cans made of polyethylene terephthalate (1) - cardboard packs.
50 pcs. - cans made of polyethylene terephthalate (1) - cardboard packs.
100 pieces. - cans made of polyethylene terephthalate (1) - cardboard packs.

pharmachologic effect

Mucolytic agent with expectorant action. Reduces the viscosity of bronchial secretions by depolarizing the acidic polysaccharides it contains and stimulating the secretory cells of the bronchial mucosa, which produce secretions containing neutral polysaccharides. It is believed that bromhexine promotes the formation of surfactant.

Pharmacokinetics

Bromhexine is rapidly absorbed from the gastrointestinal tract and undergoes intensive metabolism during the “first pass” through the liver. Bioavailability is about 20%. In healthy patients, Cmax is determined after 1 hour.

Widely distributed in body tissues. About 85-90% is excreted in the urine, mainly in the form of metabolites. The metabolite of bromhexine is.

The binding of bromhexine to plasma proteins is high. T1/2 in the terminal phase is about 12 hours.

Bromhexine penetrates the BBB. In small quantities it penetrates the placental barrier.

Only small amounts are excreted in urine with T1/2 6.5 hours.

The clearance of bromhexine or its metabolites may be reduced in patients with severe hepatic or renal impairment.

Indications

Diseases of the respiratory tract accompanied by the formation of difficult-to-discharge viscous secretions: tracheobronchitis, Chronical bronchitis with a broncho-obstructive component, cystic fibrosis, chronic pneumonia.

Contraindications

Hypersensitivity to bromhexine.

Dosage

Orally for adults and children over 10 years old - 8 mg 3-4 times a day. Children under 2 years of age - 2 mg 3 times a day; at the age of 2 to 6 years - 4 mg 3 times a day; at the age of 6 to 10 years - 6-8 mg 3 times a day. If necessary, the dose can be increased for adults to 16 mg 4 times / day, for children - up to 16 mg 2 times / day.

In the form of inhalations, adults - 8 mg, children over 10 years old - 4 mg, aged 6-10 years - 2 mg. At the age of up to 6 years - used in doses of up to 2 mg. Inhalations are carried out 2 times a day.

The therapeutic effect may appear on days 4-6 of treatment.

Side effects

From the outside digestive system: dyspeptic symptoms, transient increase in the activity of liver transaminases in the blood serum.

From the side of the central nervous system:, dizziness.

Dermatological reactions: increased sweating, skin rash.

From the respiratory system: cough, bronchospasm.

Constantly heard, it belongs to the group of drugs with an expectorant, mucolytic effect. Available in different forms(tablets, syrup). Patients have almost no questions with the liquid form of the medicine.

For what purpose are Bromhexine tablets prescribed, the specifics of use according to the instructions are constantly discussed topics.

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Classmates

Composition and pharmacological action

Bromhexine tablets contain the main component and a number of additional ones. Namely:

the role of the active component lies with bromhexine hydrochloride;
The positions of auxiliary elements are allocated to lactose monohydrate, sugar, stearic acid, potato starch, and microcrystalline cellulose.

Bromhexine tablets are prescribed to patients of all age groups. Including young children.

Bromhexine is characterized by rapid absorption into the blood through the walls of the gastrointestinal tract. Once in the blood, the active substance is transported to the cells of the respiratory organs. After the effect has been produced, the metabolic products of the drug are excreted in the urine (mostly). Action medicine has three directions:

mucolytic;
expectorant;
antitussive (to a lesser extent).

Bromhexine hydrochloride acts on secretory cells (lysosomes) of the mucous tissues of the respiratory organs. This leads to the active production of surfactant, which restores the normal functioning of the alveoli of the lungs. In addition, the active component of the drug accelerates the process of reducing viscosity, separating mucus and removing it from the body. Available in dosages of 4 mg and 8 mg of active substance per tablet. The package can contain 10-100 pieces.

Recipe in Latin

Bromhexine (tablets) is available in pharmacies without a prescription. In this case, it happens that the doctor writes down a list of drugs for treatment in Latin. So, a prescription in Latin for an adult patient will look like:

Rp. Tab. Bromhexini 0.008;
D.t.d. N. 20;
S. 2 tablets 3-4 times a day per os.

The children's dosage in the instructions for use differs from that for adults. Recipe in Latin for Bromhexine tablets for a child:

Rp. Tab. Bromhexini 4mg;
D.t.d. N. 50;
S. 1 tablet 3 times a day per os.

For the layman, it is useful to know what is meant by abbreviations. Here Rp. - this is “take”, D. t. d - “dispense the indicated dose”, S. (signa) - “prescription”, Tab. – “tablets”, per os – “orally”.

What are these pills for?

Liquefaction and removal of mucus from the respiratory system eliminates cough.

However, taking into account how many diseases are accompanied by this symptom, I would like to get more accurate information: what do Bromhexine tablets help with? Indications for prescribing the drug are diseases:

(, broncho-obstructive component);
tracheobronchitis;
bronchial type of asthma;
in a chronic form;
cystic fibrosis;
pneumoconiosis;

According to the instructions for use, Bromhexine is used for bronchopulmonary diseases accompanied by the formation of sputum with high levels viscosity

What kind of cough does it help with?

Additionally, it is important to understand what type of cough Bromhexine tablets are effective for. This information is not fully included in the instructions for use.

We are talking about two main types of the symptom under discussion: dry and wet. The first type manifests itself in:

frequent attacks;
absence of sputum discharge;
acute pain in the throat and, sometimes, chest.

To eliminate it, you will need to activate the separation of sputum from the tissues of the respiratory organs. It is also important to ensure its rapid removal.

A wet cough has almost the opposite manifestation. Namely:

rare attacks;
secretion of sputum with each cough;
The expectorated mucus is easily spat out.

Depending on the stage of the disease, the color of the sputum varies from clear to cloudy or reddish red due to blood inclusions.

The summary of the drug Bromhexine (tablets), given in the instructions for use, states that active substance The medication stimulates the production, reduction of viscosity and separation of sputum. In other words, the cough becomes more severe, but effective. The organs of the respiratory system are faster freed from mucus and pathogens/viruses. Thus, Bromhexine helps eliminate both types of cough.

Instructions for use for adults

Instructions for use Bromhexine (in tablets) recommends that adult patients take at least 8 mg of the active substance 3-4 times a day. At regular intervals. The exact dosage regimen is determined by the attending physician.

How to use?

Instructions for using Bromhexine tablets provide several basic recommendations for patients. These include:

intake is carried out regardless of food consumption;
the minimum number of uses per day is three times;
The tablet must be taken with a sufficient amount of water;
increase the amount you drink clean water up to 2-3 liters.

Dosage

The standard dosage of Bromhexine in tablets, provided for in the instructions for use, for an adult patient is 3-4 tablets of 8 mg each (total 24-32 mg) per day.

Depending on the intensity of the symptom, the dosage of bromhexine hydrochloride will increase to 48 mg for 24 hours.

In severe cases of the disease, the instructions for use allow doubling the dose. Then the patient is prescribed 2 tablets 4 times a day (total 64 mg) at regular intervals. The effect of the drug occurs within 24-72 hours.

Important Notes

Detailed information about the required dosage of the drug, as well as how to take Bromhexine tablets, should be provided to the patient by the attending physician. Based on the individual health status, the specialist writes a prescription and outlines a dosage regimen. In addition, regular monitoring of the patient’s well-being throughout the course of treatment is necessary.

Review Reviews

Reviews of Bromhexine tablets from doctors and patients can be summarized in a single list, omitting personal details. So, opinions look like:

the drug is one of best options by price-quality ratio;
certainly effective against wet cough;
does not always help with dry cough without appropriate support;
For some patients, it is difficult to drink more water;
doctors note the danger of self-treatment with the drug;
Experts draw attention to the need to first determine the cause of cough.

Bromhexine tablets show excellent results when used according to indications and according to a doctor’s prescription. Otherwise, you can get complications of the current disease and manifestations side effects.

What to choose - tablets or syrup?

When talking about which type of drug to choose for internal use - tablets or Bromhexine syrup, it is worth taking into account the characteristics of a particular patient.

When it comes to treating a child, it is much easier to use and has a gentler effect. Also, this type of drug has a softening and antitussive effect, which is suitable for dry cough.

If the emphasis is on quick and productive treatment, tablets will give the best results. The high rate of dissolution of the drug and its absorption into the blood, as well as a large dosage of the active substance, will relieve cough better and in the shortest possible time.

Analogs

It is not always possible to find the right drug in pharmacies. In this case, you can purchase an analogue of Bromhexine in tablets. This is about:

Solvine;
Bromhexine MS;
Bromhexine Obolenskoe;
Bromhexine Grindes;
Bromhexine-UBF;

The list of analogue medicines is constantly expanding. You can find a suitable option based on the active ingredient.

Bromhexine is a universal drug, which is very important when the disease affects a child. To achieve the best effect, it is better to have several methods of influence. This is why the product, available in the following forms, is so valued:

tablets;
syrup;
solution for inhalation;
solution for injection.

The most popular form of Bromhexine for younger patients is syrup. Its use relieves irritation and relieves cough. At the same time, this type of drug is most effective on initial stages diseases.

The standard dosage of Bromhexine for children, provided for in the instructions for use, includes 4 mg of the active substance 3-4 times a day. In severe cases, the dosage changes to 8 mg 3 times a day or 16 mg 2 times a day.

Useful video

Why is it important to diagnose the cause of a cough? Watch the doctor's advice in the following video:

Conclusion

Regardless of the forms in which Bromhexine is produced, this drug is on the list of the most effective in the fight against cough. Tablets are the best option for oral administration. The benefits of using them include:

speed of impact on the body;
a large dose of the active substance in one tablet;
convenient form for use, transportation and storage.

To completely get rid of the disease, it is important to strictly follow the instructions of your doctor and the recommendations of the instructions for use. The patient must regularly take all prescribed medications and adhere to the agreed regimen.

If your health worsens during treatment, you must immediately stop using the medications and seek medical advice. medical care. If symptoms persist after the course, additional examination and adjustment of the treatment program will be required.

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Bromhexine: instructions for use and reviews

Latin name: Bromhexine

ATX code: R05CB02

Active substance: Bromhexine

Manufacturer: JSC "Pharmasintez", JSC "Dalkhimfarm", LLC "Yodillia-Pharm", JSC "PFK Obnovlenye", LLC "Bioreactor", JSC "Valenta Pharmaceuticals", JSC "Pharmstandard-Leksredstva", JSC "HFK Akrikhin", JSC "Vifitech", JSC "Biosintez" (Russia)

Updating the description and photo: 12.08.2019

Bromhexine is a mucolytic agent with an expectorant effect.

Release form and composition

Tablets 8 mg (in cell packs and jars of various packaging);
Tablets for children 4 mg (in blisters of 10 pieces);
Oral solution 4 mg/5 ml (in bottles of 100 ml);
Syrup 4 mg/5 ml (in bottles of 60 and 100 ml).

The active ingredient of the drug is bromhexine hydrochloride.

Pharmacological properties

Pharmacodynamics

Bromhexine is a prodrug that is converted into ambroxol in the body. The drug enhances the activity of lysosomes of goblet cells, which are part of the epithelium of the respiratory tract. This leads to the release of lysosomal enzymes responsible for the hydrolysis of mucoproteins and mucopolysaccharides. Bromhexine hydrochloride activates the production of surfactant and neutral polysaccharides, and also normalizes mucociliary clearance. This compound ensures the dilution of bronchial secretions of increased viscosity and stickiness and its removal from the bronchi. Bromhexine is characterized by an antitussive effect.

Pharmacokinetics

Bromhexine penetrates the placental and blood-brain barriers. It binds to plasma proteins by 99%. There is also a “first pass” effect through the liver, in which the biotransformation of the active component of the drug occurs with the formation of an active metabolite - ambroxol. The therapeutic effect becomes noticeable within 20-30 minutes after ingestion. The half-life is 6.5 hours, increasing in chronic renal failure. Bromhexine is excreted through the kidneys in the form of metabolites by approximately 85-90% and tends to accumulate in the body.

Indications for use

The use of Bromhexine is advisable in the treatment of respiratory diseases, the course of which is associated with the formation of a difficult-to-discharge viscous secretion:

Chronic bronchitis with a broncho-obstructive component;
Tracheobronchitis;
Bronchial asthma;
Chronic pneumonia;
Cystic fibrosis.

Contraindications

A contraindication to the use of the drug is increased sensitivity patient to bromhexine.

Instructions for use of Bromhexine: method and dosage

Bromhexine solution, tablets and syrup are taken orally.

The dosage is determined based on the patient’s age:

Children under 2 years of age are recommended to take 2 mg 3 times a day;
Children from 2 to 6 years old – 4 mg 3 times a day;
Children from 6 to 10 years old – 6-8 mg 3 times a day;
Children over 10 years of age and adults - 8 mg 3 times a day;
If necessary, the dose can be increased: for adults - up to 16 mg 4 times a day, for children - up to 16 mg 2 times a day.

Use of the drug in the form of inhalations:

Children under 6 years old - up to 2 mg 2 times a day;
Children from 6 to 10 years old - 2 mg 2 times a day;
Children over 10 years old - 4 mg 2 times a day;
Adults - 8 mg 2 times a day.

The therapeutic effect usually appears on days 4-6 of use. The duration of treatment ranges from 4 to 28 days.

Parenteral administration is used in severe cases and in the postoperative period, in order to prevent the accumulation of thick sputum in the bronchi. The drug is administered (intravenously or intramuscularly) 2-3 times a day, 2 mg slowly over 3 minutes.

Side effects

From the central nervous system: dizziness and headaches;
From the respiratory system: bronchospasm, cough;
From the digestive system: transient increase in the activity of liver transaminases in the blood serum, dyspeptic manifestations;
Dermatological reactions: skin rash, excessive sweating.

Overdose

When taking too high doses of Bromhexine, symptoms such as diarrhea, dyspepsia, nausea, and vomiting may occur. In this case, symptomatic treatment is recommended.

special instructions

When treating patients suffering from gastric ulcers, as well as persons with a history of gastric bleeding, the use of the drug should be carried out under the supervision of a physician.

For patients diagnosed with bronchial asthma, Bromhexine is prescribed with caution.

Bromhexine can be used as part of combination drugs plant origin containing essential oils (including menthol, eucalyptus oil, peppermint, anise).

Use during pregnancy and lactation

According to the instructions, Bromhexine in any dosage form contraindicated in the first trimester of pregnancy. In the second and third trimesters, the drug can be prescribed after a thorough study of the balance between the benefits of therapy for the mother and the potential risks for the fetus. During the course of treatment with Bromhexine, breastfeeding must be stopped.

Drug interactions

When Bromhexine is combined with antitussive drugs, difficulty in sputum discharge may occur due to a weakening of the cough reflex. The drug is pharmaceutically incompatible with alkaline solutions (pH more than 6.3).

Analogs

Analogues of Bromhexine are:

for tablets: Solvin, Bromhexine MS, Bromhexine Obolenskoe, Bromhexine-Egis, Bromhexine-UBF;
for solution: Bromhexine-Egis, Bromhexine Nycomed, Bromhexine 4 Berlin-Chemie;
for syrup: Bronchostop, Bromhexine-Acree.

Terms and conditions of storage

The shelf life of tablets and syrup is 5 years, solution – 3 years. Store in a dry place, protected from light and out of reach of children. Store syrup and tablets at a temperature no higher than 25 °C, solution – no higher than 30 °C.

Bromhexine Berlin Chemie instructions for use refer to drugs that stimulate the motor function of the respiratory tract and secretolytics. Tablets 4 mg and 8 mg, syrup, solution have mucolytic, expectorant and bronchodilator effects. Reviews from patients and recommendations from doctors indicate that this medicine helps in the treatment of cough, including dry cough, bronchitis and asthma.

Release form and composition

Bromhexine is available in the following dosage forms:

Tablets 8 mg (in cell packs and jars of various packaging).
Syrup 4 mg/5 ml (in bottles of 60 and 100 ml).
Tablets for children 4 mg (in blisters of 10 pieces).
Oral solution 4 mg/5 ml (in bottles of 100 ml).

The active ingredient of the drug is bromhexine hydrochloride.

pharmachologic effect

Bromhexine reduces the viscosity of bronchial secretions, as it depolarizes the acidic polysaccharides it contains and stimulates the secretory cells of the bronchial mucosa, which produce secretions containing neutral polysaccharides.

The main active ingredient, bromhexine hydrochloride, provides a weak antitussive effect. The drug thins mucus, increases its volume and stimulates discharge. It also improves the formation of surfactant, which stabilizes alveolar cells during the respiratory process.

The effect of taking the medicine becomes noticeable 2-5 days after starting treatment. Taking Bromhexine tablets and other forms of release of the drug does not lead to its accumulation in the body; it is excreted mainly by the kidneys in the urine, mainly in the form of metabolites.

What does Bromhexine Berlin Chemie help with?

Indications for the use of the drug include diseases of the respiratory tract, the course of which is associated with the formation of a difficult-to-discharge viscous secretion:

Cystic fibrosis.
Chronic bronchitis with a broncho-obstructive component.
Tracheobronchitis.
Chronic pneumonia.
Bronchial asthma.

Instructions for use

Bromhexine tablets and solution are taken orally:

adults and children over 10 years old - 8 mg 3-4 times a day;
children under 2 years of age - 2 mg 3 times a day;
at the age of 2 to 6 years - 4 mg 3 times a day;
at the age of 6 to 10 years - 6-8 mg 3 times a day.

If necessary, the dose can be increased for adults to 16 mg 4 times a day, for children - up to 16 mg 2 times a day.

Parenteral administration is recommended for treatment in severe cases, as well as in the postoperative period to prevent the accumulation of thick sputum in the bronchi. Administer 2 mg subcutaneously, intramuscularly or intravenously 2-3 times a day slowly over 2-3 minutes.

Contraindications

Before taking Bromhexine in tablets or syrup, you should familiarize yourself with the contraindications to its use. Absolute contraindications include:

personal hypersensitivity;
lactation;
peptic ulcer of the gastrointestinal tract in the period of exacerbation;
pregnancy in the first trimester;
sugar intolerance;
children up to 2 years old for syrup and up to 6 years old for tablets.

Side effects

Bromhexine is usually well tolerated. However, in rare cases, some unwanted effects may occur:

angioedema;
dizziness;
anaphylactic reactions;
Stevens-Johnson syndrome;
increased cough;
diarrhea;
hives;
Lyell's syndrome;
increased aminotransferase activity in the blood;
dyspeptic disorders;
nausea;
exacerbation of peptic ulcer of the duodenum and stomach;
bronchospasm;
vomit;
breathing disorder;
increased sweating;
stomach pain;
skin rashes;
skin itching;
headache;
chills;
anaphylactic shock.

Children, pregnancy and breastfeeding

Prescribed if the expected benefit to the mother exceeds the expected risk to the fetus or child.

Syrup and tablets are contraindicated in children under 2 years of age. Due to the specific dosage, it is advisable for children under 6 years of age to take syrup; those over 6 years of age should take syrup and tablets for children.

special instructions

When treating patients suffering from gastric ulcers, as well as persons with a history of gastric bleeding, the use of the drug should be carried out under the supervision of a physician. For patients diagnosed with bronchial asthma, Bromhexine is prescribed with caution.

It is not recommended to take the medicine simultaneously with drugs that contain codeine, which is explained by the difficulty of coughing up liquefied sputum. Bromhexine can be used as part of combination preparations of plant origin containing essential oils (including menthol, eucalyptus oil, peppermint, anise).

Drug interactions

Do not prescribe in parallel with antitussive drugs (for example, codeine-containing ones), due to difficulty in the discharge of bronchial secretions.

Combined use with NSAIDs can irritate the gastrointestinal mucosa and even lead to the formation of erosions and ulcers.

The use of Bromhexine favors the penetration of sulfonamide drugs and antibiotics (Oxytetracycline, Erythromycin, Amoxicillin, Cephalexin) into the bronchial secretions in the first 4-5 days of antibiotic therapy.

Analogues of the drug Bromhexine

Analogues are determined by structure:

Vero-Bromhexine.
Phlegamine.
Bromhexine Berlin-Chemie (MS; Grindeks; Nycomed; -Ruspharm; -Akri; -Egis;).
Solvin.
Flexoxin.
Bronchotil.

Analogues of action include:

Acestine.
Acetylcysteine.
Fluditek.
Fluimucil
Ascoril.
AmbroHexal.
Libexin.
Bronchosan.
Flavamed.
Bronchoxol.

Vacation conditions and price

The average price of Bromhexine (8 mg tablets No. 50) in Moscow is 30 rubles.

Available without a prescription. Should be stored in a dry place, protected from light, at a temperature not exceeding 25 °C. Shelf life – 5 years.

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"Bromhexine" is a drug that is used for the treatment of acute and chronic diseases accompanied by difficult to separate sputum. Main release form medicinal product- pills.

The drug "Bromhexine" (tablets). Instructions: description, pharmacokinetics

The drug contains the active substance bromhexine. Auxiliary components: lactose monohydrate, sugar, calcium stearate, starch.

The drug is well absorbed in the stomach and intestines, then undergoes metabolic transformation in the liver. The drug is distributed throughout all tissues of the body. It is excreted by the kidneys in the form of inactivated compounds. The half-life of the drug components reaches two hours. The drug is able to penetrate into the brain tissue through A small part of it can enter the fetus through the placenta. The release of drug components may slow down if renal function is impaired.

Medicine "Bromhexine" (tablets). Instructions for use: pharmacodynamics

The drug has a pronounced expectorant and weak antitussive effect. Mucolytic effects are associated with liquefaction and depolymerization of mucopolysaccharide and mucoprotein fibers. One of the most important features of the drug’s action is the stimulation of the synthesis of endogenous surfactant. It also increases the activity of the ciliated epithelium.

The drug "Bromhexine Berlin-Chemie" (tablets). Instructions: method of application, dosage

Oral administration is the only way to use this medicine. It is consumed regardless of meals. For adults, the dose is four tablets three times in one day. During therapy, it is recommended to consume a sufficient amount of water, which maintains the secretolytic activity of the drug. The maximum treatment period is four weeks.

Medicine "Bromhexine" (tablets). Instructions: side effects

Among the numerous side effects, the most common are increased activity of liver transaminases, which is transient in nature, headache, increased sweating, cough, skin rash, and bronchospasm.

The drug "Bromhexine" (tablets). Instructions: contraindications, drug interactions

The drug should not be used if there is hypersensitivity to the components, peptic ulcer disease (acute stage), or during pregnancy. It is also contraindicated for use in children under six years of age.

It is allowed to prescribe this drug in combination with drugs from other groups that are used to treat bronchopulmonary diseases. It promotes the penetration of antibiotics into the lung tissue. Use together with codeine is unacceptable, as this leads to difficulty coughing up sputum. The drug is used in combination with herbal preparations, essential oils. Use together with alkaline solutions is also unacceptable.

Medicine "Bromhexine" (tablets). Instructions: special instructions, overdose

For patients with impaired renal function, this drug is prescribed in slightly lower doses. If bronchial motility is weak and there is a significant amount of mucus secretion, the use of the drug requires special caution, as this may cause retention of contents in the bronchi. Bronchial, asthma, gastric ulcers are diseases for which the drug should be used under the supervision of a doctor. The drug is used during lactation and pregnancy only in rare cases.

Symptoms of overdose: vomiting, nausea, intestinal disorders. To date, no specific antidote for this drug has been developed. Therefore, all therapy in case of overdose comes down to gastric lavage, which should be carried out within the first two hours after consuming the drug.