Artrosilene ointment instructions for use. Indications, analogues and instructions for the use of artrosilene injections. Interaction with other drugs

Artrosilene is a drug from the group of non-steroidal anti-inflammatory drugs. The active component is the substance ketoprophenalysine salt.

Unlike ketoprofen, salt does not have an irritating effect on the gastrointestinal tract and is better tolerated by patients.

The drug is available in the form of a gel for external application, capsules for oral administration, a solution for intramuscular and intravenous administration, rectal suppositories, and a spray.

Pharmacological effects

Artrosilene is used in the complex treatment of diseases of the spine and joints. Artrosilene helps to provide analgesic, antipyretic and anti-inflammatory effects. The use of the drug can reduce morning stiffness, eliminate swelling of the damaged joint and increase its mobility.

Contraindications

General contraindications for the use of all medicinal groups the drug Artrosilene are:

individual intolerance to the active or excipients of the drug;
development of aspirin-induced asthma;
breastfeeding period;
the presence of gastric and duodenal ulcers (acute phase) or peptic ulcers;
development of ulcerative colitis (acute stage) or Crohn's disease;
bleeding disorders, including hemophilia;
development of chronic renal failure.

Interaction with other drugs

When using the drug Artrosilene, its possible interaction with other groups of drugs should be taken into account.

With the simultaneous use of Artrosilene with ethanol, barbiturates, rifampicin, tricyclic antidepressants, the metabolism of the active substance of the drug increases.

The drug may have an effect on reducing the effectiveness of antihypertensive drugs and diuretics; enhance the effect of drugs from the group of anticoagulants and antiplatelet agents.

There is a possibility of increased unwanted side effects corticosteroids and estrogens when used simultaneously.

Due to its pharmacological effect, the drug Artrosilene can mask the manifestations of infectious diseases.

Use of the drug by patients with a history of bronchial asthma may cause suffocation.

During treatment with Artrosilene, you should refrain from operating transport mechanisms, as well as performing work that requires increased concentration.

Atrosilene gel

Artrosilene gel is used in the treatment of acute and chronic inflammatory diseases musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the spine and joints, rheumatic lesions of soft tissues.

The drug is also used for muscle pain of rheumatic and non-rheumatic etiology and for traumatic injuries of soft tissue.

It is recommended to use the gel no more than 3 times a day. The drug is applied with gentle rubbing movements and wait until the drug is completely absorbed. The exact dosage, duration and frequency of use of the medicine is determined by the doctor, taking into account the nature of the damage and accompanying symptoms of the disease. If there is no effect from the therapy, a re-examination and a change in the treatment strategy are recommended.

Without the knowledge of the doctor, the gel cannot be used for more than 10 days.

Side effects, contraindications

Artrosilene gel can provoke the development of allergic reactions: itching, rash, hives, redness. The gel can increase the sensitivity of the skin to ultraviolet radiation. Therefore, during therapy you should avoid being in direct sunlight, as well as visiting solariums. With prolonged use of the gel, the risk of developing systemic side effects increases.

Artrosilene in gel form cannot be used for aspirin-induced asthma, in the 3rd trimester of pregnancy, as well as in childhood up to 6 years old. Contraindications also include the presence of weeping dermatoses, eczema and violation of the integrity of the skin.

The drug in gel form is used with caution in the 1st and 2nd trimester of pregnancy, under the age of 12 years, in case of severe disturbances in the normal functioning of the liver and gastrointestinal tract.

If it is necessary to use the gel during lactation, you should consider stopping breastfeeding.

Artrosilene in the form of injections

Parenteral use of the drug should not be long-term. The maximum duration of use of the solution for parenteral administration is no more than 3 days. Then you should switch to the oral form of the drug Artrosilene in capsule form or use suppositories.

Intravenous administration of the drug can only be carried out in a hospital setting. In order to increase the exposure time of the active component, slow intravenous infusions are recommended.

The duration of the procedure is at least half an hour. The infusion is prepared using sodium chloride, Ringer's solution, and levulose solution.

An aqueous solution of the drug can be used during physiotherapeutic procedures: iontophoresis, mesotherapy.

If parenteral use of the drug Artrosilene is required in patients of older age groups, it is recommended to use the lowest effective dosage.

Indications

Indications for the use of Artrosilene injections are short-term complex therapy for the following diseases:

diseases of the musculoskeletal system of various origins;
postoperative period to reduce pain;
recovery period after injuries and severe inflammatory processes.

Contraindications

The drug is used with caution by patients with a history of diabetes mellitus, in the 1st and 2nd trimester of pregnancy, in case of anemia, alcoholism and smoking, sepsis, and heart failure.

Atrosilene spray

It is recommended to use artrosilene in spray form no more than 3 times a day. The medicine should be rubbed in carefully and wait until completely absorbed. The drug can be used during the iontophoresis procedure. In this case, the medicine is applied to the negatively charged pole.

Information regarding drug interactions of Artrosilene spray with other groups of drugs is not provided.

Artrosilene in aerosol form should be applied only to intact, undamaged skin. Avoid contact of the drug with mucous membranes and eyes. To prevent unwanted photosensitivity reactions, you should avoid exposure to direct sunlight while using the drug.

This medicine cannot be used for weeping dermatoses, in the 3rd trimester of pregnancy and in patients under 6 years of age. The drug is prescribed with caution for ulcerative lesions of the stomach and duodenum, bronchial asthma, patients of older age groups and children under 12 years of age.

Analogues, cost

Analogs of the drug Artrosilene are the following drugs: Arketal Rompharm, Flamax, Fastum, Bystrumcaps, Bystrumgel, Febrofid, Ketonal, Ketoprofen, Ketonal Duo.

The cost of the drug Artrosilene for the period August 2017 is formed as follows:

Rectal suppositories 160 mg, 10 pcs. – 350-400 rub.
Solution for intravenous and intramuscular administration 160 mg/2 ml, 6 pcs. – 180-250 rub.
Solution for intravenous and intramuscular administration 80 mg/ml, 6 pcs. – 260-370 rub.
Capsules for oral administration 320 mg, 10 pcs. – 380-420 rub.
Gel for external use 5% - 290-430 rub.
Spray for external use 15% - 480-630 rub.

You can purchase the drug with delivery throughout Moscow and Russia, for example, at the pharmacy Pill.ru.

The drug Artrosilene is produced by pharmacological companies in several dosage forms. Considered as a non-steroidal anti-inflammatory drug. It has a pronounced analgesic, antipyretic and anti-inflammatory effect.

Dosage form

The drug Artrosilene is produced in several dosage forms:

rectal suppositories;
capsules for oral administration;
solution for intravenous and intramuscular administration;
aerosol;
gel for external use.

Description and composition

The product, produced in capsule form, contains lysine salt as an active component.

The list of excipients can be presented as follows:

povidone;
diethyl phthalate;
Actic acid polymers;
diacrylic acid polymers;
carboxypolymethylene;
talc;
Magnesium stearate.

The shell contains:

titanium dioxide;
gelatin;
indigotine;
Choline yellow dye.

Gelatin capsules have an oblong shape. Each capsule contains yellow to white granules.

The active ingredient of the solution intended for intramuscular and intravenous administration is lysine salt. The list of auxiliary components can be presented as follows:

citric acid;
sodium hydroxide;
water for injections.

The solution intended for injection is transparent. the liquid is odorless.

Suppositories intended for rectal use contain an active component. Semi-synthetic glycerides act as excipients. Suppositories have a soft texture and torpedo-shaped shape.

The gel intended for external use contains the following excipients:

carbomer;
trolamine;
polysorbate;
ethanol;
methyl parahydroxybenzoate;
purified water.

List of auxiliary components. contained in the aerosol can be represented in the following form:

propylene glycol;
polysorbate;
lavender-neroli flavor;
povidone;
mixture of gases;
benzyl alcohol;
purified water.

Regardless of the release form, all Artrosilene drugs have the same active substance.

Pharmacological group

Nonsteroidal anti-inflammatory drugs for oral, intravenous and external use.

Indications for use

The list of indications for use of the drug can be presented as follows:

mild to moderate pain that occurs after surgical interventions and injuries;
inflammatory pain;
rheumatoid arthritis;
spondyloarthritis;
gouty arthritis;
inflammation of the periarticular tissue.

for adults

The drug is used by patients of this age group. The drug is well tolerated; elderly patients and people with liver problems require dose adjustment.

for children

Drugs for systemic use are contraindicated for use in pediatric practice. Formulations in the form of a gel and aerosol for external use can be used by patients over the age of 6 years.

Using the products significantly reduces the likelihood of egg implantation, so women planning a pregnancy should refrain from using the composition. The product is not recommended for use in. In the initial stages, the composition can be used as prescribed by a doctor, but the woman’s condition must be constantly monitored. When using the product during breastfeeding It is recommended to transfer the baby to artificial nutrition.

Contraindications

The list of contraindications for use can be presented as follows:

peptic ulcers;
Crohn's disease;
peptic ulcer;
aspirin triad;
disorders of blood clotting processes;
chronic renal failure;
lactation period;

The drug is also contraindicated in patients with hypersensitivity to its individual components.

Applications and dosages

The dosage regimen and release form are selected individually for each patient, depending on the available indications for use.

for adults

Doses are determined depending on the indications for use. The permissible dose when used in the form of rectal suppositories is 480 mg per day. When using the composition in capsule form - 500 mg per day.

for children

Doses of drugs for external use, as well as the frequency and duration of their use, are determined individually.

for pregnant women and during lactation

The composition during pregnancy can only be used as prescribed by a doctor.

Side effects

Adverse reactions often occur with the use of Arthroxylene. The list of possible ones includes:

abdominal pain;
digestive disorders;
esophagitis;
gastritis;
duodenitis;
erosive and ulcerative lesions of the gastrointestinal tract;
hematomesis;
melena;
high levels of bilirubin;
hepatitis;
liver enlargement;
dizziness;
mood swings;
hallucinations;
increased anxiety;
irritability;
malaise;
visual impairment;
acute allergic reactions;
disturbances in the urinary system;
disturbances in the functioning of the hematopoietic system;
disorders in the respiratory system;
pathologies of the cardiovascular system.

When using the compositions in external forms, local allergic reactions may occur.

Interaction with other drugs

Data about drug interactions Containing drugs from other groups should be checked with your doctor.

special instructions

During the course of therapy with Artrosilene, it is necessary to constantly monitor the picture of peripheral blood and the functional state of the liver and kidneys. It is worth considering that while using the composition, symptoms of infectious processes may not appear.

Artrosilene is used with special caution by patients with bronchial asthma; the compositions can cause an attack of suffocation. When using the products, you should avoid potentially dangerous activities that require increased concentration.

Overdose

Until now, cases of overdose with Artrosilene drugs have not been recorded in therapeutic practice. If symptoms of overdose occur and a significant deterioration in the patient’s well-being is recommended, symptomatic treatment is recommended. If the patient's condition worsens, hospitalization is necessary. There is no specific antidote, hemodialysis is ineffective.

Storage conditions

Medicines produced in the form of capsules, injection solution and gel for external use should be stored at a temperature of no more than 25 degrees. The drug in aerosol form should be protected from exposure to direct sunlight. Rectal suppositories should be stored in the refrigerator.

Medicines should be kept away from children. The shelf life for the products is 3 years from the date of production. Medicinal preparations Artrosilene are dispensed from a network of pharmacies for free sale.

Analogues

There are drugs that can replace Artrosilene. some of them are inferior to the drug in activity, but significantly superior to it in terms of pricing. Many of the products are cheaper. A doctor will help you choose a high-quality and affordable analogue if it is not possible to purchase Artrosilene, because when making an independent choice, the patient may make a mistake.

The drug has similar properties and is a structural analogue of the drug Artrosilene. In most cases, the drug is well tolerated and is the most adequate substitute. produced in various release forms. The use of the drug in pediatric practice is limited. The composition is not used during pregnancy and breastfeeding.

– a medicine produced by pharmacological companies in the form of a solution for intravenous administration, as well as in the format of tablets and capsules for oral administration. The active substance is. The composition is not used during pregnancy and breastfeeding. The medicine can be prescribed to adolescents over the age of 15 years.

Price

The cost of Artrosilene is on average 285 rubles. Prices range from 150 to 596 rubles.

Artrosilene is a drug from a number of NSAIDs. Main medicinal substance this tool is the lysine salt of ketoprofen. This substance is much better tolerated by patients than diclofenac-containing tablets, since it does not have a negative effect on the mucous membrane of the gastrointestinal tract.

For ease of treatment, Artrosilene is produced in various forms:

Artrosilene gel for surface use;
capsules;
suppositories for rectal use;
injection solutions;
Artrosilene spray for cutaneous use.

Effects of the drug

Each of the pharmacological forms of Artrosilene has anti-inflammatory, analgesic and antipyretic effects. The use of this remedy increases the motor ability of the diseased joint, reduces the manifestation of joint stiffness in the morning, and eliminates swelling in the area of inflammation.

Lysine salt dissolves quickly, so it does not have an aggressive effect on the gastrointestinal tract. External use of the drug allows you to enhance the effect of the drug locally at the site of the lesion. The effect is enhanced by the combined use of several forms of Artrosilene.

When is the drug prescribed?

This product in the form of suppositories or capsules is recommended for the following conditions:

moderate joint pain associated with surgery, injury or inflammation;
arthritis of gouty or rheumatoid origin;
osteoarthritis;
spread of the inflammatory process to the soft tissues adjacent to the joints;
spondyloarthritis.

Injection forms of Artrosilene are prescribed for severe pain syndrome for a short course of therapy for the following pathologies:

pathologies of the musculoskeletal system in the acute phase of inflammation;
post-traumatic or post-operative pain syndrome.

Forms for external use are prescribed for chronic pain of low intensity or as an addition to the main treatment for the following conditions:

injuries of soft tissue structures;
muscle pain of various etiologies;
diseases of the osteoarticular system, accompanied by inflammatory and destructive processes in the joints.

It is worth noting that contraindications to the prescription of this drug may differ slightly, depending on the pharmacological form of release. Let's consider the conditions for which it is not recommended to use this medicine in any form:

pregnancy and breastfeeding;
Crohn's disease or ulcerative colitis;
diverticulitis;
“aspirin” asthma;
severe renal failure;
individual intolerance to the components of the drug;
peptic ulcer or peptic ulcer;
hemophilia and other blood pathologies.

eczema;
weeping type dermatosis;
skin damage.

Particular caution is required when using Artrosilene in patients with the following diagnoses:

liver failure;
chronic heart failure;
anemia;
alcoholism;
bronchial asthma;
diabetes.

Side effects of the drug on the body

Side effects from the use of Artrosilene, taking into account patient reviews, may be different. However, they all appear based on individual characteristics body. Most often, according to patient reviews, undesirable effects associated with the use of the drug manifest themselves in the form of dysfunction:

sense organs;
heart and blood vessels;
nervous system;
respiratory organs;
liver;
genitourinary organs;
hematopoietic organs.

When using forms for external use, allergic rashes, photosensitivity or other skin reactions are possible. If any side effect is detected, specialist consultation and treatment adjustment are required.

How to use Artrosilene?

Instructions for use of the drug are attached to each package of the drug, regardless of the release form. Artrosilene can be used in several ways: orally, rectally, externally and by injection.

Capsules are prescribed 1 piece per day after meals. Treatment involving the use of this medicine in capsule form can last about 3-4 months. Taking into account patient reviews, capsules are the most convenient form of taking the drug. However, the use of capsules in the treatment of chronic pathologies of the osteoarticular system is accompanied by uncontrolled medication intake. Although no cases of drug overdose have been recorded, it should be remembered that indefinitely long-term use of capsules can provoke serious complications.

The injection form of Artrosilene is intended for intravenous or intramuscular administration into the patient's body. The frequency of administration is also once a day. Injections are chosen for a short course of treatment lasting up to 3 days. If further treatment is necessary, it is recommended to switch to capsules or suppositories.

Suppositories can be used up to 2-3 times throughout the day. For elderly patients, it is not recommended to use Artrosilene in this form more than 2 times a day.

Forms for surface use are usually used up to 3 times a day. The aerosol dosage for a single use is 1-2 g. The duration of such treatment should be no more than ten days.

Features of application

When used in treatment regimens suppositories, capsules or injections, indicators should be periodically monitored general analysis blood, as well as renal function and liver performance (biochemical studies).
Treatment with this drug may reduce the severity clinical manifestations infectious disease.
In case of decreased liver and kidney function, it is recommended to reduce the dose of the drug.
The drug can significantly reduce the ability of an egg to implant, so the course of treatment should be interrupted before planning a pregnancy.
If it is necessary to determine the level of 17-ketosteroids in the body, you should stop taking the drug at least two days before the analysis.
External forms of Artrosilene can be applied only to undamaged skin.
This drug enhances the effect of substances and drugs such as: heparin, vitamin K antagonists, antithrombotics, ethanol alcohol, drugs with lithium, glucocorticoids, methotrexate, hypoglycemic drugs.

Artrosilene's analogs

Analogues of the drug include the following:

Bystrumcaps;
Ketonal Duo;
Arketal;
Bystrumgel;
Ketoprofen;
Fastum;
Rompharm;
Febrofeed;
Flamax.

Despite the abundance of analogues, you still shouldn’t choose a replacement for Artrosan on your own. You should not rely on positive reviews about the drug on the Internet or the approval of the pharmacist. To select an analogue, it is better to consult a doctor.

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The drug Artrosilene, which contains the main active ingredient Ketoprofen, is widely used in inflammatory processes of periarticular tissues, accompanied by increased pain.

Artrosilene is available in various forms:

capsules for oral administration;
injections for intramuscular and intravenous injections;
gel for external use;
aerosol applied externally;
suppository for rectal use.

pharmachologic effect

Being a non-steroidal anti-inflammatory drug, Artrosilene stops chronic inflammatory processes, inhibiting the activity of enzymes that destroy tissue, inhibits the synthesis of prostaglandins, inhibits COX-1 and COX-2.

Having a slight negative effect on the gastrointestinal tract, the drug gives a good therapeutic result, acts as an analgesic, and has an antipyretic effect.

Thanks to the effects of the drug, patients gain the opportunity to develop the necessary range of movements, stiffness disappears after a period of rest, and tissue swelling decreases. When administered orally, the maximum effect is observed after 4 hours.

The effect of external drugs is analgesic, anti-edematous, they are used as an anti-inflammatory for lesions of joints and soft tissues: muscles, tendons, ligaments.

Pharmacokinetics of the drug

The absorption of the oral form of the drug in capsules gives the maximum effect after 4 hours, the durability of the result depends on the dose of the drug taken, bioavailability exceeds 80%, when administered parenterally, the maximum concentration in the synovial fluid appears after one hour, and the therapeutic effect lasts longer than when using other forms, up to 24 hours.

When used rectally, the degree of absorption of the drug and the manifestation of the therapeutic effect are also high, and when used externally, the drug is absorbed slowly, the bioavailability is 5%.

By binding to plasma proteins, the active substance ketoprofen is well distributed in organs and tissues, in synovial fluid, and in connective tissue. Metabolism of the drug occurs in the liver. Metabolic products are excreted by the kidneys within 24 hours.

Indications for use

Depending on the form, Artrosilene is used in the following cases:

Used internally capsules and suppositories used as analgesics for postoperative conditions, for pain due to overload or for moderate pain indicating the presence of inflammation in the periarticular tissues. Drugs are prescribed for various types, inflammation.
Solutions for injections are used to relieve acute pain and for postoperative pain, inflammation of periarticular tissues of various origins.
Gels and aerosols more often used for soft tissue lesions and injuries; for osteoarthritis of the spine, for muscle pain of a non-rheumatic nature.

Contraindications for use

Contraindications for taking any form of the drug are:

individual intolerance to the active substance, hypersensitivity to it or to other non-steroidal anti-inflammatory drugs;
aspirin asthma;
peptic ulcer and ulcerative colitis, Crohn's disease;
diverticulitis;
hemophilia and other blood clotting disorders;
chronic renal failure;
lactation period.

Children's age is a contraindication for the use of the drug in all forms except gel and aerosol.

During pregnancy, the drug is prescribed with caution only as an external agent in the third period of pregnancy.

Mechanism of action

The active substance of the drug ketoprofen, containing 99%, penetrates the blood plasma, binding to albumin and distributed in tissues, inhibiting the synthesis of prostaglandins and inhibiting COX-1 and COX-2, inhibiting the activity of pathogenic enzymes.

How to use the medicine?

Depending on the form of release, the instructions for use of Artrosilene also differ.

The drug is produced:

More details about dosages

Use Artrosilene orally during or after meals for 3 or 4 months, one capsule per day.

Intravenously or intramuscularly in a slow administration mode, intravenously 500 ml over 30 minutes, one ampoule no more than twice a day for 3 days.

Injections are performed in a hospital. Prepared solutions should be used immediately.

1 suppository is applied rectally 2-3 times a day, the maximum dose per day is no more than 480 mg.

Externally, the drug is used in an amount corresponding to the area of the painful surface, but no more than 5 g per application when using a gel and no more than 2 g when using an aerosol; this is the size of a pea and the volume of a teaspoon, respectively, for a course of no more than 10 days.

In case of overdose

If you suspect an excess permissible dose of the drug, respiratory and cardiac activity should be monitored, and if violations are detected, symptomatic therapy should be provided.

Side effects

Occurring while taking the drug side effects can be characterized by the following changes:

the digestive system suffers from ulcerative disorders, the patient experiences abdominal pain and diarrhea;
the hematopoietic system reacts by increasing the level of bilirubin and increasing the activity of liver enzymes, the size of the liver exceeds the norm;
the nervous system reacts with general malaise, involuntary tremor, anxiety;
lacrimation and vision problems may occur;
various types of skin allergies;
cystitis, hematuria. disruption of the menstrual cycle;
bronchospasm, laryngeal spasm, rhinitis;
tachycardia, swelling, hyper- and hypotension.
allergic reactions: anaphylactoid reactions, swelling of the oral mucosa, pharyngeal edema, periorbital edema.

Allergic reactions to suppositories may appear several hours after administration of the drug: itching, burning, a feeling of heaviness, hemorrhoids and its aggravation.

If the patient’s condition worsens while taking the drug or the above symptoms appear, it is necessary to urgently consult a doctor.

special instructions

When applied externally, skin dermatoses and eczema may also occur. For bronchial asthma, the drug is prescribed with caution, as well as in old age.

Capsules and solutions are not used for anemia, diabetes, sepsis, edema, high blood pressure, stomatitis, children under 12 years of age.

Capsules, dissolving for administration and suppositories are contraindicated in alcoholism.

In case of severe dysfunction of the liver and kidneys, the drug is not prescribed.

Internally taken medications are contraindicated during lactation. Also contraindicated in the third period of pregnancy.

Gels and aerosols are used in the first and second periods of pregnancy if necessary under the supervision of a doctor.

Internally acting drugs are not prescribed to persons under 18 years of age. Gels and aerosols are used after the patient reaches 12 years of age.

Interaction with other drugs

Barbiturates and tricyclic antidepressants enhance the activity of ketoprofen.

The effect of anticoagulants increases, the effect of diuretics decreases, and the side effects of glucocorticoids increase.

Concomitant administration with other anticoagulants increases the risk of bleeding.

Strengthens the effect of insulin, the dose must be calculated differently. Affects platelet production.

Let's study a qualified opinion

Review from a doctor who uses Artrosilene in his practice.

When prescribing a drug, we carefully study the patient's medical history. We are monitoring whether he has diseases of the hematopoietic organs or others.

The drug works flawlessly and has already helped hundreds of sick people. The course of taking capsules lasts up to 4 months. Injections should not be taken for a long time.

Doctor of the orthopedic clinic, Khanaev V.P.

Pain in the back, lower back, and joints push people to use medications of various dosage forms. It is important to start treatment promptly and correctly, and not to eliminate only pain syndromes. Contacting a specialist will help you find out which drug is suitable for this particular case. Artrosilene is an anti-inflammatory drug that comes to the aid of various joint diseases (arthritis, arthrosis and other diseases).

Artrosilene contains ketoprofen, which is a lysine salt. It is the main substance that affects the source of pain. The remaining substances included in the drug are auxiliary. The medication is a non-steroidal anti-inflammatory drug that helps reduce pain.

The use of Artrosilene is noticeable when the feeling of joint stiffness and swelling decreases and motor activity increases.

Artrosilene is presented in several forms on the pharmaceutical market:

Capsules (internal use) - one pack contains 10 pieces of 160 mg each;
Ointment (external use) - tube of 30 g or 50 g;
Rectal suppositories - 10 suppositories in one pack;
Ampoules for injection - one pack contains 6 pieces, ampoule volume - 2 ml;
Aerosol spray (for external use, has a lavender scent) - bottle volume 25 ml.

The country of origin of the drug Artrosilene is Italy. INN - Ketoprofen.

Capsules and injections can be purchased at any pharmacy with a prescription issued by the attending physician, and suppositories and gels - without a prescription.

Price medicinal product Artrosilene varies depending on the form of release on the market, as well as on the dosage:

Artrosilene: indications for use

In the presence of a disease with an acute or chronic inflammatory course, the drug Artrosilene is often prescribed. The therapeutic result is expressed as follows:

Reduced swelling and swelling;
Relieving pain;
Increased motor ability of the affected area;
Decrease in temperature.

Doctors of various specialties (gynecologists, dentists, neurologists, oncologists and others) can prescribe the use of Artrosilene. Indications for use are usually the following diseases:

Seeing a doctor is key aspect for the patient, since it is the doctor who will be able to prescribe the correct treatment regimen and choose the current dosage form. For prescribing capsules and suppositories as treatment

Artrosilene is based on the following indicators:

Prick injections can be prescribed by a doctor in the presence of acute pain for quick response:

Inflammatory pain of a post-traumatic nature;
Diseases of the skeletal and muscular systems.

Aerosols and gels will be prescribed by a physician if:

Soft tissue damage due to trauma;
Diseases of the musculoskeletal system (arthritis, osteoarthritis, ankylosing spondylitis);
Rheumatic muscle pain.

Artrosilene: instructions for use

Artrosilene does not cure the disease itself, but only helps relieve discomfort. It is effective to use the medication in combination with other medications. The combination of drugs can only be prescribed by highly qualified medical personnel.

The drug Artrosilene is absorbed human body without significant losses, which indicates high level bioavailability:

Artrosilene has a gentle effect on cartilage tissue, which allows the patient to use this medication for a long time.

Dosages depending on the form of release of the medicine on the pharmaceutical market:

The capsule form of Artrosilene is taken orally with or after meals. You should take no more than 1 capsule per day. The course of treatment can last about 3-4 months to achieve a therapeutic effect.
Injections can be administered intramuscularly or intravenously. The maximum dosage is 1 ampoule twice a day. Administration of the medication intravenously at home is prohibited. This procedure can only be performed by medical personnel in a hospital setting. The solution is injected into the vein slowly. People of retirement age should reduce the dosage to 1 ampoule per day. The solution cannot be stored after opening the ampoule. The duration of treatment is no more than 3 days.
Artrosilene suppositories can be prescribed by a doctor, 1 piece twice a day. The highest dose per day is 3 suppositories (480 mg per day). Patients of retirement age are recommended to use no more than 2 suppositories per day.
The use of a gel or ointment is usually done “by eye”, i.e. you need to squeeze out a volume the size of a large berry from the tube.
Aerosols and sprays are applied to the painful area. The spray application area should be the size of Walnut" Then it must be slowly rubbed into the skin. For external use, Artrosilene can be used for at least 10 calendar days.

The effectiveness of using Artrosilene depending on the dosage form:

Artrosilene: contraindications for use

Like any medicine, Artrosilene has a number of contraindications for use:

Chronic renal failure;
Sensitivity and allergic reactions to substances included in the drug;
Bleeding disorders;
Pregnancy and breastfeeding;
Diseases of the gastrointestinal tract (ulcerative colitis);
Aspirin asthma;
Diverticulitis;
Young age (up to 15 years).

The use of ointments and gels for external use is permitted for children over 6 years of age.

Ointments, gels, aerosols and sprays Artrosilene cannot be used if you have:

Skin diseases (eczema, dermatitis, wounds).

Artrosilene should be used with caution in any dosage form, if there are:

Artrosilene: side effects

In some cases, taking Artrosilene leads to side effects:

The use of suppositories sometimes causes exacerbation of hemorrhoids and burning in the anus.

Artrosilene: pros and cons of the drug

The positive aspects of the drug Artrosilene include:

High level of bioavailability;
Quite fast action of the drug;
A wide range of release forms (gel, capsules, aerosol, suppositories, ointments).

Negative characteristics of Artrosilene include:

High price.

Artrosilene: combination with other medications

Artrosilene is not compatible in combination with tramadol solution. Reduces the effectiveness of diuretics and also enhances the effect of anticoagulants. Concomitant use of Artrosilene with thrombolytics increases the risk of internal bleeding.

The medication enhances the effect of insulin, so diabetics should take this drug with extreme caution. The dosage should be confirmed only with the attending physician.

Storage conditions

Artrosilene is stored in dark place, unattainable for children. Temperature- no more than 25°C. The duration of use of suppositories and capsules is no more than 5 years after release on the pharmaceutical market, and injections, gels and aerosols are up to 3 years.

Analogues

The pharmacological market is filled with medications varying in cost and composition. Artrosilene has a number of “synonym analogues” - drugs that have a similar composition and strength of action on the pain site.

Artrosilene analogues (generics):

Artrosilene and Ketoprofenal: comparison

Difference between medications:

The decision on the choice of medication and its dosage for a particular case is made only by the attending physician.

Artrosilene and Ketonal: comparison

Differences between medications:

Artrum and Artrosilene: comparison

Difference between medicines:

Artrosilene and OKI: comparison

Comparison of analogue medicines by key indicators:

Both drugs are foreign and manufactured in Italy.

The combined use of Artrosilene and alcoholic beverages leads to the risk of developing gastrointestinal bleeding, and also increases the strength of the medication several times.

Alcohol can be consumed:

8-14 hours before taking the medicine;
18-24 hours after taking the medication.

Artrosilene, when taken simultaneously with alcoholic beverages, can enhance negative impact on the liver, and also increases the risk of developing gastrointestinal ulcers. There may be periodic occurrence of severe headaches, noise in the ear canals, and a feeling of general weakness.

If you find that taking alcohol and Artrosilene has caused one or more of the listed side effects, then you must:

Stop drinking alcohol immediately;
Drink as much clean water as possible within 4 hours.

If Artrosilene (regardless of the form: gel, aerosol or capsules) is used for a long course, then drinking alcohol is prohibited from 3 days to 1 calendar month. The ban period alcoholic products You can check with your doctor.