Neuromultivitis side effects in adults. Neuromultivitis: instructions for use, analogues and reviews, prices in Russian pharmacies. Contraindications to the use of Neuromultivit

Neuromultivit is a pharmacological agent containing B vitamins, indicated for use in pathologies of the nervous system.

What are the composition and release form of Neuromultivit?

The active ingredients of the pharmaceutical product Neuromultivit are represented by the following vitamins: cyanocobalamin - 200 micrograms, thiamine hydrochloride in an amount of 100 mg and pyridoxine hydrochloride, the content of which is 200 mg.

Excipients of the drug: hypromellose, macrogol 6000, povidone, titanium dioxide, microcrystalline cellulose, magnesium stearate, talc.

The medicine Neuromultivit is available in tablets white with darker inclusions. Sold in packs of 20 pieces. Dispensed by pharmacies upon presentation of a prescription.

What are the effects of Neuromultivit?

All active substances of the drug contribute to the normalization of the nervous system, both central and peripheral. The combined therapeutic effect of all three vitamins is more than three times greater than the effectiveness of each individual active substance.

Thiamine is a stimulant of metabolic reactions occurring in the nervous system. Provides. It influences the processes of electrical impulse transmission, participating in the reactions of neurotransmitter biosynthesis.

Cyanocobalamin is involved in the processes of synthesis of nucleic acids, stimulates the reactions of regeneration and renewal of biological tissues, normalizes the lipid composition of nervous tissue, and improves the patient’s mental abilities.

Pyridoxine is required for the normal functioning of the nervous system, since it acts as a coenzyme in the formation of neurotransmitters (dopamine, norepinephrine, gamma-aminobutyric acid). In addition, vitamin B6 regulates metabolic processes occurring in most tissues and organs.

All components of the Neuromultivit drug are water-soluble compounds and, as a result, they do not have the ability to accumulate. An overdose of the drug is unlikely. However, exceeding the recommended dosage will not affect the severity of the pharmacological action.

The use of the drug helps improve functional, eliminates painful sensations, normalizes the patient’s mental abilities, improves sleep, increases tolerance physical activity, prevents the development of serious complications of neurological pathology.

When taken orally, the processes of absorption of active substances occur in the small intestine. The biological transformation of vitamins occurs in the liver. Excretion occurs in stool and urine. As the dosage increases, excess active ingredients are excreted in the bile.

Indications for use

Taking the vitamin preparation Neuromultivit is indicated in the following cases:

Trigeminal neuralgia;
Intercostal neuralgia;
Shoulder pain syndrome;
Radicular syndrome;
Polyneuropathy of various etiologies and pathogenesis;
Osteochondrosis with neurological symptoms.

It is necessary to focus attention on an important circumstance. The drug is not a conventional multivitamin indicated for the treatment of hypovitaminosis. This is a medicine for the treatment of neurological pathologies.

Contraindications for use

The instructions for use prohibit taking Neuromultivit (tablets) in the following cases:

The patient's age is 18 years or less;
Hypersensitivity to the components of the pharmaceutical product.

In addition, pregnancy and lactation.

Application and dosage

The dosage of the drug should be selected by the attending physician. The effective dose of the medicine is in the range from 1 to 3 tablets per day. To prevent irritation of the gastric mucosa, it is recommended to take the pharmaceutical product after meals.

The duration of therapeutic measures depends on the opinion of the specialist, but in any case, treatment should not last more than 4 weeks, especially if patients take significant amounts of the drug.

Side effects

Taking Neuromultivit tablets can provoke the development of the following side effects: nausea, vomiting, heaviness and bloating, loose stools or constipation, headache, dizziness, allergic reactions on the skin.

special instructions

Treatment of neurological patients with this drug is not recommended in combination with multivitamin pharmaceuticals. The joint use of pharmaceuticals by representatives of these groups creates the preconditions for the development of an overdose.

The drug may reduce the antiparkinsonian activity of the pharmaceutical drug levodopa. To adjust the dosage, you need to consult your doctor.

Analogs

Neurorubin, Nerviplex, Neurotrat forte, Neurobex, Vitaxon, . Analogs can be used only after prior consultation with your doctor, since there may be a discrepancy between contraindications and dosages.

Conclusion

Treatment of pathology of the nervous system should be carried out under the close supervision of an experienced specialist, with mandatory adherence to an integrated approach consisting of the following measures: taking pharmaceuticals recommended by the doctor, a balanced diet, complete exclusion of smoking and alcohol abuse, and a good night's rest.

In addition, it is important to avoid working at night, and it is also necessary to periodically visit your doctor to adjust the dosages of medications taken.

Neuromultivit is a combined patented multivitamin drug. The drug was developed and produced by the Austrian company Lannacher Heilmittel.

What forms of release can be found in Russia?

Neuromultivit in our country is sold in the form of tablets and ampoules. The fundamental difference between each form lies in the area of ​​application, that is, the drug, produced in the form of a solution, is used in cases where it is impossible to use a tablet product. What are the indications for use of neuromultivitis, are there any contraindications, composition and instructions for use in our article.

Being a complex drug, Neuromultivit includes three vitamins belonging to the vitamin group B. Namely, pyridoxine, thiamine, cyanocobalamin.

Vitamin B1 or thiamine hydrochloride is necessary for the proper functioning of metabolic processes - carbohydrate, protein and lipid. It is also directly involved in the process of impulse transmission in nerve endings.

Or pyridoxine hydrochloride is a substance that is necessary for the proper functioning of the nervous system, both central and peripheral. With his participation in human body a number of substances are synthesized, without which the normal course of many nervous processes would be impossible. For example, norepinephrine, adrenaline, dopamine.

Or cyanocobalamin is also necessary for the normal functioning of the nervous system. In addition, this substance is necessary for the maturation of red blood cells and for the implementation of many metabolic processes.

Each Neuromultivit tablet contains 100 mg of thiamine hydrochloride, 200 mg of pyridoxine hydrochloride, 200 mcg of cyanocobalamin. The tablet has a film shell of almost white color.

When is the drug indicated?

As a rule, Neuromultivit is prescribed in complex therapy of many neurological diseases, that is, in combination with other drugs. Thus, the use of this drug is indicated for people suffering from polyneuropathy, which can have different origins. Including for the treatment of diabetic and alcoholic polyneuropathy.

Other indications for use of Neuromultivit:

  • lumbago;
  • neuralgia of various localizations;
  • intercostal neuralgia;
  • neuritis;
  • sciatica;
  • plexitis;
  • facial nerve paresis;
  • radicular syndrome, which can be caused by a degenerative process in the spine;
  • inflammation of the trigeminal nerve.

Are there any contraindications?

Like any drug, there are contraindications to the use of Neuromultivit, but there are very few of them. The drug should not be prescribed to people who are allergic to at least one component of its composition.

Pediatric use this tool Allowed only for therapy who are over 12 years old.

It is not advisable to prescribe Neuromultivit to pregnant women at any stage, as well as to breastfeeding mothers.

How to use the drug correctly?

The main thing is that The film-coated tablet must be taken whole. It should not be crushed or chewed, otherwise the effectiveness of this drug will be significantly reduced. Neuromultivit should be taken immediately after meals. You need to drink it with water, you can also use tea for this.

The dosage of the drug is selected by the doctor depending on the severity of the disease, as well as the presence of concomitant pathology. Prescribe it one tablet one to three times a day. The duration of the course is determined by the doctor, however its use for more than 4 weeks is undesirable.

How much does a vitamin complex cost?

Of course, depending on the city or pharmacy where you purchase the drug, its price may vary. On average across the country, a package of Neuromultivit, which contains 20 tablets, costs from 171 to 302 rubles. A package of 60 tablets costs 503 - 612 rubles.

Experts' opinion

Antipova T. M, pharmacist. Today, the drug Neuromultivit is one of the most accessible B-vitamin products. Everyone knows what vitamin deficiencies in group B mean for a person. These are irritability, nervousness, brittle nails. And the complex vitamin preparation Neuromultivit is in a good way strengthening the nervous system.

What do patients say?

Anna, 35 years old. She slept poorly and was irritable. I was very exhausted at work. Then a friend recommended Neuromultivit and I decided to take it. Started taking the drug with caution. At first I took one tablet a day, and after about 10 days I noticed that I began to fall asleep quickly and my sleep became deeper. I continue taking the medicine, I wonder what will happen next.


Alexander Petrovich, 58 years old. My review is rather positive. I read the neuromultivit readings and was surprised by the impressive list. I myself have neuralgia, which I have been suffering from for a long time. I tried everything, but it didn’t help. So I decided to take Neuromultivit, and after one month I noticed that the pain was no longer so strong. I think I will continue taking the pills.

Neuromultivitis in ampoules

Each ampoule of the drug contains a solution in a volume of 2 ml. The solution contains the same active substances as the tablet form. Namely, pyridoxine hydrochloride, thiamine hydrochloride, cyanocobalamin. There are also excipients - water for injection, diethanolamine. Cyanocobalamin in the amount of 1 mg, pyridoxine hydrochloride 100 mg, thiamine hydrochloride 100 mg.

When is the drug used?

  • neuralgia of different localization;
  • neuritis;
  • radiculoneuritis arising as a result of degenerative diseases of the spine (vertebral syndrome, cervical syndrome and others);
  • intercostal neuralgia;
  • inflammation of the trigeminal nerve;
  • sciatica.

Contraindications to the use of the liquid form of Neuromultivit similar to those described above. But, nevertheless, they have some differences:

  • allergy to the main or auxiliary components of the drug;
  • erythrocytosis and erythremia;
  • hypervitaminosis;
  • children under 12 years of age;
  • pregnancy;
  • lactation.

Correct Application

Administration of the drug is allowed only into the muscle. Only in the gluteal muscle according to the rules. For mild cases of the disease, the neurologist prescribes one injection two or three times a week. In severe or acute conditions, one ampoule is prescribed daily until the syndrome is relieved.

The average price of Neuromultivit in ampoules is about 220 rubles.

Experts' opinion

Uchelkina L. A., pharmacist. I can recommend the combined drug Neuromultivit, which contains three vitamins from group B. It should be used as part of a complex treatment of various neurological diseases. It has a beneficial effect on nerve endings and the entire system.

Instructions

The multivitamin drug "Neuromultivit" is prescribed as part of complex therapy for the following diseases of the nervous system: neuralgia, neuritis, plexitis, intercostal neuralgia, sciatica, lumbago, trigeminal neuralgia, diabetic and alcoholic polyneuropathy, degenerative pathologies of the spine with radicular syndrome. The drug is released in coated containers. One tablet contains vitamin B1 (100 mg), vitamin B6 (200 mg) and vitamin B12 (0.20 mg). The drug stimulates metabolism in the nervous system, improves recovery processes in nervous tissue, and also has some analgesic effect.

The peculiarities of the mechanism of action of the drug are determined by its components. Vitamin B1 in the body is converted into cocarboxylase, which takes part in many metabolic processes, and also participates in the processes of transmission of nerve impulses in nerve endings (synapses). Vitamin B6 is required for the normal functioning of the nervous system and takes part in the synthesis of many neurotransmitters (dopamine, norepinephrine, histamine, etc.). Vitamin B12 is involved in hematopoiesis, metabolism, and is necessary for the body for the processes of cell division and growth.

Take Neuromultivit after meals with water, 1 tablet. 1-3 times a day. The duration of therapy is determined by the doctor, usually it is 2-4 weeks. The drug has a therapeutic effect within 1-2 weeks after starting administration. It is not recommended to take Neromultivit for longer than 4 weeks. The drug is contraindicated in hypersensitivity to the components of the product during pregnancy and lactation. Side effects the medicine causes in rare cases. These include: nausea, itching, rash, tachycardia.

Neuromultivit reduces the effectiveness of antiparkinsonian drugs medicines(“Levodopa”). Ethanol intake sharply reduces the absorption of vitamin B1. While using the medicine, it is not recommended to take other drugs containing B vitamins. Analogues of Neuromultivit are: Angiovit, Sana-Sol, Pikovit, Vitacitrol, Viabex, Revit, Milgamma , “Neurogamma”, “Kombilipen”, “Unigamma”, “Kaltsevita”, “Neurotrat forte”. The drug should be replaced with an analogue only after consultation with a doctor. Neuromultivit is stored in a dark, dry place out of reach of children. The storage temperature should not be higher than 25 °C. The shelf life of the product is 3 years.

Neuromultivit is a combination drug containing B vitamins: B1, B6, B12.

Produced in 2 forms:

  • Tablets for internal use are white, film-coated. Each package of the drug contains 20 or 60 tablets;
  • The solution for intramuscular injections is red. Packaged in 2 ml ampoules made of dark glass. Each package contains 5 ampoules.

Manufacturer Pharma GmbH (Austria). The fundamental difference between each form lies in the area of ​​application - the drug, produced in the form of a solution for injections, is used in cases where the use of tablets is impossible and an immediate effect is required.

  1. Vitamin B1 or thiamine hydrochloride is necessary for the proper functioning of metabolic processes - carbohydrate, protein and lipid. It is also directly involved in the process of impulse transmission in nerve endings.
  2. Vitamin B 6 or pyridoxine hydrochloride is a substance that is necessary for the proper functioning of the nervous system, both central and peripheral. With its participation, a number of substances are synthesized in the human body, without which the normal course of many nervous processes would be impossible. For example, norepinephrine, adrenaline, dopamine.
  3. Vitamin B12 (cyanocobalamin) plays an important role in hematopoiesis and the formation of red blood cells, and is also involved in many metabolic processes in the body - the synthesis of nucleic acids, phospholipids and cerebrosides. Cyanocobalamin as a coenzyme is necessary for the processes of cell division and growth.

The active components of Neuromultivit are characterized as low-toxic substances, so taking the drug is not associated with a potential risk to humans.

Indications for use

What does Neuromultivit help with? The drug is prescribed in the following cases:

  • polyneuropathy of various etiologies (including diabetic, alcoholic);
  • intercostal neuralgia;
  • trigeminal neuralgia;
  • radicular syndrome caused by degenerative changes spine;
  • cervical syndrome;
  • glenohumeral syndrome;
  • lumbar syndrome;
  • lumboischialgia.

Instructions for use Neuromultivit, dosage

Injections

The drug is administered intramuscularly, deeply. The first 5-10 days, 2 ml \ 1 time per day.

The duration of therapy is determined by the attending physician. If treatment is continued, switch to less frequent injections - 2 to 3 times a week. The course should not exceed 2-3 weeks.

  • Intravenous administration of the drug is not allowed!

When using Neuromultivit injections, the patient must be under the supervision of a physician. It is recommended to switch to using tablets as soon as possible.

Instructions for tablets

The drug is used only after meals. The prescribed dose should be swallowed whole, not chewed, and washed down with at least 50 ml of clean water.

The recommended dosage is 1 Neuromultivit tablet once a day. The duration of the course of treatment in most cases is 1 month. If continued therapy is required, dose reduction options should be considered.

In severe cases, you should take 1 tablet \ 3 times a day until the condition improves. Taking time should be distributed evenly throughout the day: in the morning (before lunch), after lunch and in the evening. In the future, they switch to using standard therapeutic doses.

Side effects

Prescription Neuromultivit may be accompanied by the following side effects:

  • nausea,
  • tachycardia,
  • skin reactions in the form of itching and urticaria.

Clinical symptoms of an overdose of vitamins included in the drug can occur only after taking extremely high doses for a very long time.

  • Vitamin B6 - after taking more than 2 g/day, neuropathies with ataxia and sensory disturbances, convulsions with EEG changes and, in some cases, hypochromic anemia and seborrheic dermatitis have been described.
  • Vitamin B12 – after parenteral administration (in rare cases, after oral administration), eczematous skin changes and acne were observed.

Due to the fact that the drug contains vitamin B6, Neuromultivit should be prescribed with caution in patients with a history of gastric and duodenal ulcers, as well as with severe kidney and/or liver dysfunction.

Contraindications

Neuromultivit is contraindicated in the following cases:

  • Hypersensitivity to the components of the drug.
  • Vitamin B1 is contraindicated for use in allergic diseases.
  • Vitamin B6 is contraindicated for use in case of peptic ulcer of the stomach and duodenum in the acute stage (since it is possible to increase the acidity of gastric juice).
  • Vitamin B12 is contraindicated for use in cases of erythremia, erythrocytosis, and thromboembolism.

Overdose

With prolonged use of Neuromultivit or accidentally ingesting a large number of tablets, patients develop signs of overdose, which are expressed by the following clinical signs:

  • neuropathy;
  • ataxia;
  • heart rhythm disturbance;
  • seborrheic dermatitis;
  • convulsions;
  • changes in indicators on the electrocardiogram;
  • development of hypochromic anemia;
  • eczematous rashes.

If these symptoms appear, treatment with the drug should be stopped, and if necessary, the patient is given symptomatic therapy.

Analogues of Neuromultivit, price in pharmacies

If necessary, you can replace Neuromultivit with an analogue of the active substance (B vitamins) - these are the drugs:

  1. Angiovitis,
  2. Neurobion,
  3. Vitacytrol,
  4. Kaltsevita,
  5. Unigamma.

When choosing analogues, it is important to understand that the instructions for use of Neuromultivit, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not independent replacement drug.

Price in Moscow pharmacies: Neuromultivit No. 20 tablets - 270 rubles, 2 ml solution 5 ampoules - 188 rubles, 2 ml solution 10 ampoules - from 337 to 380 rubles.

Store in a dry place, protected from light. Keep away from children. The temperature should not exceed 25C. Dispensed in pharmacies by doctor's prescription.

Neuromultivit - the latest description of the drug, you can see contraindications, indications for use, dosage of the Neuromultivit medication. Useful reviews about Neuromultivitis -

Vitamin B complex.
Drug: NEUROMULTIVIT®
Active substance of the drug: cyanocobalamin, pyridoxine, thiamine
ATX encoding: A11DB
KFG: Vitamin B complex
Registration number: P No. 013734/01
Registration date: 12/29/06
Owner reg. cred.: LANNACHER HEILMITTEL Ges.m.b.H. (Austria)

Neuromultivit release form, drug packaging and composition.

White or almost white, film-coated tablets, round, biconvex.

1 tab.
thiamine hydrochloride (vit. B1)
100 mg
pyridoxine hydrochloride (vit. B6)
200 mg
cyanocobalamin (vit. B12)
200 mcg

Excipients: microcrystalline cellulose, magnesium stearate, povidone, macrogol 6000, titanium dioxide, talc, hypromellose, Eudragit NE30D (methacrylic acid and ethacrylate copolymer).

20 pcs. — cellular contour packages (1) — cardboard packs.

The description of the drug is based on the officially approved instructions for use.

Pharmacological action Neuromultivit

Thiamine (vitamin B1) in the human body, as a result of phosphorylation processes, is converted into cocarboxylase, which is a coenzyme of many enzymatic reactions. Thiamine plays an important role in carbohydrate, protein and fat metabolism. Actively participates in the processes of nerve excitation in synapses.

Pyridoxine (vitamin B6) is necessary for the normal functioning of the central and peripheral nervous system. In its phosphorylated form, it is a coenzyme in the metabolism of amino acids (including decarboxylation, transamination). Acts as a coenzyme for the most important enzymes operating in nerve tissues. Participates in the biosynthesis of neurotransmitters such as dopamine, norepinephrine, adrenaline, histamine and GABA.

Cyanocobalamin (vitamin B12) is necessary for normal hematopoiesis and maturation of red blood cells, and is also involved in a number of biochemical reactions that ensure the vital functions of the body (in the transfer of methyl groups, in the synthesis of nucleic acids, proteins, in the metabolism of amino acids, carbohydrates, lipids). It affects processes in the nervous system (RNA, DNA synthesis) and the lipid composition of cerebrosides and phospholipids. The coenzyme forms of cyanocobalamin—methylcobalamin and adenosylcobalamin—are essential for cell replication and growth.

Pharmacokinetics of the drug.

The components of the drug are water-soluble vitamins, which eliminates the possibility of their accumulation in the body.

Suction and distribution

Thiamine and pyridoxine are absorbed in the upper intestine, the extent of absorption depends on the dose.

The absorption of cyanocobalamin is largely determined by the presence of intrinsic factor in the stomach and upper intestine; further delivery of cyanocobalamin to the tissue is carried out by the transport protein transcobalamin II.

Metabolism

Thiamine, pyridoxine and cyanocobalamin are metabolized in the liver.

Removal

Thiamine and pyridoxine are excreted by the kidneys (about 8-10% unchanged). In case of overdose, the excretion of thiamine and pyridoxine through the intestines significantly increases.

Cyanocobalamin is excreted mainly with bile, the degree of excretion by the kidneys is variable - from 6 to 30%.

Indications for use:

As part of complex therapy for the following neurological diseases:

Polyneuropathy of various etiologies (including diabetic, alcoholic);

Neuritis and neuralgia;

Radicular syndrome caused by degenerative changes in the spine;

Lumbago;

Plexites;

Intercostal neuralgia;

Trigeminal neuralgia;

Facial nerve paresis.

Dosage and method of administration of the drug.

Prescribe 1 tablet orally. 1-3 times/day. The duration of the course is determined individually.

The tablets should be taken after meals, without chewing and with a small amount of liquid.

Side effects of Neuromultivitis:

In isolated cases: nausea, tachycardia, skin reactions in the form of itching and urticaria.

The drug is well tolerated.

Contraindications to the drug:

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation.

It is not recommended to use Neuromultivit during pregnancy and lactation ( breastfeeding) due to the lack of reliable clinical data confirming the safety of the drug during these periods.

Special instructions for use of Neuromultivit.

Drug overdose:

Currently, no cases of overdose of Neuromultivit have been reported.

Interaction of Neuromultivit with other drugs.

With the simultaneous use of Neuromultivit and levodopa, a decrease in the antiparkinsonian effectiveness of levodopa is observed.

With the combined use of Neuromultivit and ethanol, the absorption of thiamine, which is part of the drug, is sharply reduced (the level in the blood can decrease by 30%).

Terms of sale in pharmacies.

The drug is available with a prescription.

Terms of storage conditions for the drug Neuromultivit.

The drug should be stored in a dry place, protected from light, out of the reach of children, at a temperature not exceeding 25°C. Shelf life: 3 years.